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南京农业大学农学院《Plant Physiology》发表华健教授课题组“CHROMATIN REMODELING 11-dependent nucleosome occupancy affects disease resistance in rice”（图）
华健 基因转录 蛋白修饰
2023/10/28
染色质重塑主要包括围绕核小体的组蛋白修饰和染色质重塑蛋白介导的染色质构型调控。染色质重塑介导的基因转录表达调控是植物基因转录调控最重要的调控机制之一。然而，目前对于病原菌侵染诱导的寄主植物核小体动态变化及其与基因转录表达的关系尚不清楚。
南京农业大学农学院《Plant Physiology》发表万建民院士团队“Phytochrome B mediates dim-light-reduced insect resistance by promoting the ethylene pathway in rice”（图）
万建民 水稻褐飞虱 基因
2023/10/28
褐飞虱是水稻生产中最严重的害虫。褐飞虱通过针状口器刺入水稻叶鞘组织吸食韧皮部汁液，造成水稻严重减产甚至绝收。种植抗性品种是综合防控褐飞虱的基础。然而植物抗病虫性通常受光照、温度和湿度等环境因素的影响，在一定程度上制约了抗性基因的有效利用。如采用密植的栽培方式是当前许多作物增加单位面积产量的重要途径，但是密植通常会导致冠层以下的植株部分光照不足而产生庇荫反应，易滋生各类病虫害，虽然这种现象普遍存在，...
MIT chemists have discovered the structure of a protein that can pump toxic molecules out of bacterial cells. Proteins similar to this one, which is found in E. coli, are believed to help bacteria bec...
Systematical characterization of YUCCA gene family in five cotton species, and potential functions of YUCCA22 gene in drought resistance of cotton
棉花 YUC基因家族 生长素合成
2024/5/17
生长素在植物的正常生长发育中起着至关重要的作用。TAA/YUCCA基因家族编码色氨酸氨基转移酶（tryptophan aminotransferase），是生长素合成的关键酶。然而，棉花中YUCCA（YUC）基因家族尚未见报道。为了揭示YUC基因在棉花中的功能，我们系统地鉴定了五个棉种中的YUC基因家族，包括成员分析、特征描述、基因组内复制和共线关系。转录组学分析表明，GhYUCs参与了棉花的非生...
Reducing antibiotic use in primary care may be insufficient alone to curtail antimicrobial resistance
antibiotics AMR E. coli primary care
2021/8/6
Strategies to reduce antibiotic prescribing in primary care are insufficient alone to halt the rise in drug resistant E. coli infections in England, a new report concludes.
Teaching CRISPR and antibiotic resistance to high school students（图）
Teaching CRISPR antibiotic resistance high school students
2019/10/30
A Northwestern University-led team funded by the National Science Foundation has developed BioBits, a suite of hands-on educational kits that enable students to perform a range of biological experimen...
Within-day protein distribution does not influence body composition responses during weight loss in resistance-training adults who are overweight
exercise weight loss muscle mass heart health protein patterning
2018/11/20
Background: Emerging research suggests that redistributing total protein intake from 1 high-protein meal/d to multiple moderately high-protein meals improves 24-h muscle protein synthesis. Over time, ...
Effects of protein supplementation combined with resistance exercise on body composition and physical function in older adults: a systematic review and meta-analysis
elderly people obesity protein supplementation resistance exercise body composition
2018/11/16
Background: Overweight and obese older people face a high risk of muscle loss and impaired physical function, which may contribute to sarcopenic obesity. Resistance exercise training (RET) has a benef...
Effects of protein supplementation combined with resistance exercise on body composition and physical function in older adults: a systematic review and meta-analysis
elderly people obesity protein supplementation resistance exercise body composition
2018/11/20
Background: Overweight and obese older people face a high risk of muscle loss and impaired physical function, which may contribute to sarcopenic obesity. Resistance exercise training (RET) has a benef...
The effect of magnesium supplementation on blood pressure in individuals with insulin resistance, prediabetes, or noncommunicable chronic diseases: a meta-analysis of randomized controlled trials
blood pressure cardiovascular diseases insulin resistance
2018/11/16
Background: To our knowledge, the effect of magnesium supplementation on blood pressure (BP) in individuals with preclinical or noncommunicable diseases has not been previously investigated in a meta-...
Do ω-3 PUFAs affect insulin resistance in a sex-specific manner? A systematic review and meta-analysis of randomized controlled trials
adults diabetes omega-3 PUFAs DHA EPA insulin resistance insulin sensitivity
2018/12/19
Background: Evidence has suggested that omega-3 (n–3) polyunsaturated fatty acids (PUFAs) improve obesity-induced insulin resistance (IR); however, results from human intervention trials have been equ...
Gut permeability is related to body weight, fatty liver disease, and insulin resistance in obese individuals undergoing weight reduction
obesity liver steatosis insulin resistance intestinal permeability gut barrier
2018/11/12
Background: Obesity and associated metabolic disorders are related to impairments of the intestinal barrier.
Objective: We examined lactulose:mannitol (Lac:Man) permeability in obese individuals with...
Interaction of an S100A9 gene variant with saturated fat and carbohydrates to modulate insulin resistance in 3 populations of different ancestries
gene-diet interaction insulin resistance SFA:carbohydrate ratio S100A9 gene type 2 diabetes
2018/12/13
Background: S100 calcium-binding protein A9 (S100A9) has previously been identified as a type 2 diabetes (T2D) gene. However, this finding requires independent validation and more in-depth analyses in...
Effect of vitamin D replacement on indexes of insulin resistance in overweight elderly individuals: a randomized controlled trial
HOMA insulin resistance prediabetes IOM RDA high-dose vitamin D
2018/12/3
Background: It is unclear whether and at what dose vitamin D supplementation affects insulin resistance (IR).
Chicken coops,sewage treatment plants are hot spots of antibiotic resistance
Chicken coops sewage treatment plants antibiotic resistance
2016/5/19
Antibiotic-resistant bacteria most often are associated with hospitals and other health-care settings, but a new study indicates that chicken coops and sewage treatment plants also are hot spots of an...