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Synthesis, structural determination, and biological activity of new 7-hydroxy-3-pyrazolyl-4H-chromen- 4-ones and their o-b-D-glucosides
Chromones pyrazoles glucopyranosyl bromide glucosylation
2010/10/15
A convenient route to synthesize some new medicinally important 7-hydroxy-3-pyrazolyl chromones (3a-i) is described. The interaction of 7-hydroxy-3-formyl chromone (1) with various substituted acetoph...
Synthesis and Biological Activity of 4-(4-Hydroxybenzylidene)-2- (substituted styryl) oxazol-5-ones and Their o-glucosides
Oxazolone a -acetobromoglucose decetylation o-glucosides antimicrobial antifungal activity
2010/4/9
The 4-(4-hydroxybenzylidene)-2-methyl oxazol-5-ones 1 were treated with various aldehydes in the presence of acetic acid to form 4-(4-hydroxybenzylidene)-2-(substituted styryl) oxazol-5-ones 2a-i, whi...
Synthesis and Biological Activity of Allosteric Modulators of GABAB Receptors. Part 4. Synthesis of Potentially Fluorescent Acridines and Conformationally Restricted N-(arylpropyl)-1-arylethylamines
Fendiline analogues acridines acridones aminotetralins aminoindanes GABA
2010/4/15
A series of 8 new derivatives of fendiline was prepared for evaluation as allosteric modulators of GABAB receptors: 4 based on acridine and 4 with restricted distance between the 2 aryl moieties.
Metal Complexes of Schiff Bases: Preparation, Characterization, and Biological Activity
2-thiophenecarboxaldehyde 2-furancarboxaldehyde 2-aminothiophenol o-phenylenediamine
2010/4/19
Metal Complexes of Schiff Bases: Preparation, Characterization, and Biological Activity.
New Complexes of Organotin(IV) 2-(N-Maleoylamino)-2-methylpropanoate: Synthesis, Spectroscopic Characterization and Biological Activity
Organotin(IV) carboxylates spectroscopic studies biological activity
2010/4/20
Organotin(IV) complexes of 2-(N-maleoylamino)-2-methylpropanoate were prepared by treating the ligand acid with diorganotin dichloride and triorganotin chloride in 1:2 and 1:1 molar ratios, respective...
Preparation, Spectroscopic Studies and Biological Activity of Mono-organotin(IV) Derivatives of Non-Steroidal Anti-inflammatory Drugs
Mono-organotin(IV) derivatives non-steroidal anti-inflammatory drugs biological activity
2010/4/20
A set of 14 mono-organotin(IV) derivatives of general formulae n-BuSnClL2 and n-BuSnL3, where `L' are various non-steroidal anti-inflammatory drugs (NSAIDs), were synthesized and structurally characte...