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Association Between Timing of Antibiotic Administration and Mortality from Septic Shock in Patients Treated with a Quantitative Resuscitation Protocol
sepsis antibiotics septic shock emergency medicine
2014/11/28
Objective We sought to determine the association between time to initial antibiotics and mortality of septic shock patients treated with an emergency department (ED) based early resuscitation protocol...
Characteristics and Outcomes of Patients with Vasoplegic Versus Tissue Dysoxic Septic Shock
sepsis septic shock hyperlactatemia lactate mortality
2014/11/28
Background: The current consensus definition of septic shock requires hypotension after adequate fluid challenge or vasopressor requirement. Some patients with septic shock present with hypotension an...
Whole blood lactate kinetics in patients undergoing quantitative resuscitation for septic shock
whole blood lactate kinetics septic shock emergency medicine
2014/11/28
Introduction We sought to compare the association of whole blood lactate kinetics with survival in patients with septic shock undergoing early quantitative resuscitation. Methods Preplanned analysis o...
One year mortality of patients treated with an emergency department based early goal directed therapy protocol for severe sepsis and septic shock: a before and after study
sepsis septic shock emergency medicine mortality
2014/11/28
Introduction Early structured resuscitation of severe sepsis has been suggested to improve short term mortality; however, no previous study has examined the long-term effect of this therapy. We sought...
Prospective External Validation of the Clinical Effectiveness of an Emergency Department-Based Early Goal-Directed Therapy Protocol for Severe Sepsis and Septic Shock
early goal-directed therapy emergency department resuscitation sepsis septic shock
2014/11/28
Objective: To determine the clinical effectiveness of implementing early goal-directed therapy (EGDT) as a routine protocol in the emergency department (ED). Methods: Prospective interventional study ...
Performance of the Mortality in emergency department Sepsis score for predicting hospital mortality among patients with severe sepsis and septic shock
sepsis septic shock mortality emergency department MEDS score
2014/11/28
Objective The aim of the study was to test if the Mortality in Emergency Department Sepsis (MEDS) score accurately predicts death among emergency department (ED) patients with severe sepsis and septic...