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From Mouse Mammary Tumor Model to New Therapeutic Method ---Mammary Tumor Development in Balb/c-Trp53+/- Mice and Magnetic Nanoparticle Induced Heating for Cancer Treatment
Breast cancer Magnetic nanoparticle Mammary gland Mouse tumor model Stem cell Thermotherapy
2014/12/10
PATHWAYS CONTRIBUTING TO DEVELOPMENT OF SPONTANEOUS MAMMARY TUMORS IN BALB/c-Trp53+/- MICE Mutation and loss of p53 function are common features among human breast cancers. We use BALB/c-Trp53+/- mice...
Probing The Regulation Of Vasculogenic Mimicry In Glioblastoma: Implications For Treatment In Patients
Health and environmental sciences Biological sciences Angiogenesis Anti-angiogenic treatment resistance Cancer Cancer stem cells Glioblastoma Vasculogenic mimicry
2014/12/10
Glioblastoma, previously known as Glioblastoma Multiforme (GBM), is a highly angiogenic tumor and is defined pathologically by its ability to create microvascular proliferations. Patients with gliobla...
Melatonin treatment protects against diabetes-ind uced functional and biochemical changes in rat aorta and corpus cavernosum
Streptozotocin Aorta Corpus cavernosum Melatonin Insulin
2014/3/31
Enhanced oxidative stress due to diabetes is accepted to lead to endothelial dysfunction, and this is known to play a key role in the
pathogenesis of diabetic vascular diseases and complications. Thi...
Antioxidative treatment prevents activation of death-receptor- and mitochondrion-dependent apoptosis in the hearts of diabetic rats
Antioxidants Apoptosis Cardiovascular disease Diabetes Lipoic acid Streptozotocin.
2014/3/31
Aims/hypothesis. The mechanisms by which glucose
injures cells of the cardiovascular system include gen-eration of reactive oxygen species and induction of
cellular apoptosis. To date, little is kno...