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We read with great interest the article by Hume et al. (1), “Low energy intake plus low energy expenditure (low energy flux), not energy surfeit, predicts future body fat gain.” The study used the ene...
Background: Skeletal muscle (SM) is an important body-composition component that remains difficult and impractical to quantify by most investigators outside of specialized research centers. A lar...
Bees make wax (lipid) from honey (carbohydrate). Pigs fatten on a grain diet. Indeed, all organisms, from bacteria to mammals, have the enzymes of de novo lipogenesis. The physiologic function of d...
Critically ill patients are characterized by a hypermetabolic state, a catabolic response, higher nutritional needs, and a decreased capacity for utilization of parenteral substrate.
The accurate measurement of food intake in children is important for assessing nutritional status.
The waist-to-hip ratio (WHR) has emerged as an important risk factor for several chronic diseases, but little quantitative information exists about its relation with energy intake and expenditure i...
The recent worldwide increase in the prevalence of childhood obesity may be due in part to a decrease in children’s physical activity levels.
Results of leptin administration in mice, rats, and humans provide a rationale for therapeutic augmentation of circulating leptin (OB protein) concentrations in obese humans; this may reduce food i...
Carbohydrate and fat may differ in their ability to support energy-requiring physiologic processes, such as protein synthesis and growth. If so, varying the constituents of infant formula might be ...
Menopause is a time of increased risk of obesity in women. The effect of menopause in African American women, in whom obesity is already highly prevalent, is unknown.
Protein-energy malnutrition (PEM) is common in connection with chronic disease and is associated with increased morbidity and mortality. Because the risk of PEM is related to the degree of illness,...
The results of previous studies indicated that energy density, independent of fat content, influences energy intake. In most studies, however, both fat content and energy density were lower than in...
The case for the energy density of foods being an important factor in regulating short-term food intake is strong (1–4). The results of classic studies of food intake in organisms ranging from blow...
Weight reduction reduces bone mineral density (BMD) and increases the risk of osteoporosis.
Lean mass and resting energy expenditure (REE) decrease with age. However, it is unknown whether age-related changes in regional lean and fat mass are responsible for the agerelated decrease in REE...

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