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Estimate of maximum expiratory flow based on the equal pressure point concept and Weibel's lung model.
The respiratory gas exchange for O2, CO2, and CO has been studied in nine healthy male subjects before, during, and after head-out water immersion. Distribution of lung perfusion and ventilation were ...
Failure of certain circulating substances to penetrate specific organs led to the concept of blood-organ barriers. Such barriers can be altered by various physical or chemical means. This report conce...
The effect of water immersion on static lung volumes and pressure-volume curves was studied in five subjects. A special container allowed measurements during nonimmersion, head-out immersion, and thor...
The effects of static lung loading in the range +20 cmH2O to -20 cmH2O was investigated in 3 male subjects breathing air during submerged exercise in the prone position at pressures ranging from 1.45 ...
Electrocardiogram (ECG), electrocorticogram (ECoG), and respiratory rate (RR) were monitored in awake, unrestrained rats during continuous exposure to 1, 3, and 5 ATA O2 until death. The RR showed a c...
The major effects of breathing dense gas during physical exercise in hyperbaric environments can be traced to high airway resistance during inspiration and expiration and especially to an increased te...
When rabbits were exposed to 60% oxygen for 21 days, arterial PaO2 showed statistically insignificant changes at 6-8 days (69 +/- 5 Torr) and 14-16 days (62 +/- 5 Torr); at 21 days the PaO2 was signif...
Static lung load (SLL), or transrespiratory pressure gradient, imposed by underwater breathing apparatus can affect breathing comfort and mechanics, especially during exertion. We examined the effects...
To investigate the possibility of lung injury after long-term saturation dives where oxygen partial pressure was kept between 42 and 50 kPa, we measured lung volumes, diffusing capacity (DLCO/VA), and...
Decompression-induced venous bubble formation has been linked to increased neutrophil counts, endothelial cell injury,release of vasoactive eicosanoids, and increased vascular membrane permeability.
Saturation diving involves exposure to elevated partial pressure of oxygen (Po2) and high pressure. The present work demonstrated that hyperoxic exposure for up to 72 h had significant effects on huma...
The complement activation product C5a may be an important mediator of tissue injury after decompression stress. This study investigated whether the administration of anti-C5a antibody may reduce chang...
With deep saturation diving a reduction in vital capacity caused by oxygen toxicity may be opposed by a training effect of respiratory muscles due to increased gas density and work of breathing. We me...
Smoke-induced lung injury in rats was assessed in terms of histopathology, gross mortality, neutrophil accumulation and as capillary leak. Administration of hyperbaric oxygen (HBO2), 2.8 atm abs for 4...

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